<p>High Soluble Programmed Death-Ligand 1 Predicts Poor Prognosis in Patients with Nasopharyngeal Carcinoma</p>
نویسندگان
چکیده
منابع مشابه
Increased programmed death ligand-1 expression predicts poor prognosis in hepatocellular carcinoma patients
PURPOSE Accumulating studies have investigated the prognostic and clinical significance of programmed death ligand-1 (PD-L1) expression in patients with hepatocellular carcinoma (HCC); however, the results were conflicting and inconclusive. We conducted a meta-analysis to combine controversial data to precisely evaluate this issue. METHODS Relevant studies were thoroughly searched on PubMed, ...
متن کاملExpression of programmed death ligand-1 predicts poor outcome in nasopharyngeal carcinoma
Programmed death ligand-1 (PD-L1) is a potentially important tumor immunotherapy target. However, whether PD-L1 expression is associated with survival in nasopharyngeal carcinoma (NPC) remains controversial. The aim of the present study was to investigate the association between PD-L1 expression and prognosis in NPC. The expression of PD-L1 was assessed in tumor specimens from 120 patients with...
متن کاملProgrammed cell death-ligand 1 expression predicts survival in patients with gastric carcinoma with microsatellite instability
Programmed death-ligand 1 (PD-L1) is expressed in a subgroup of gastric cancers that may benefit from immunotherapy. Microsatellite instability-high (MSI-H) is a potential predictive factor for response to immunotherapy targeting the PD-1 or its ligand PD-L1. The relationship between PD-L1 expression and MSI-H status remains poorly understood. In this study, we investigated PD-L1 expression in ...
متن کاملProtein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma
BACKGROUND The clinicopathologic characteristics of tumors expressing programmed death (PD-1) ligands (PD-Ls) PD-L1 or PD-L2 and their associations with common driver mutations in lung adenocarcinoma are not clearly defined, despite the progression of anti-PD-1/PD-L1 immunotherapy. METHODS PD-L1 and PD-L2 expression was measured by immunohistochemistry in 143 surgically resected lung adenocar...
متن کاملIncrease of Soluble Programmed Cell Death Ligand 1 in Patients with Chronic Hepatitis C
Objectives: To determine whether the soluble programmed cell death ligand 1 (sPD-L1) levels in patients with chronic hepatitis C (CHC) are associated with the clinical features of the disease and the efficacy of treatment, including interferon (IFN)-α. Methods: We investigated the sPD-L1 levels in the sera of 80 genotype 1b Japanese patients with CHC who underwent 12 weeks of telaprevir (TVR)- ...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2020
ISSN: 1178-6930
DOI: 10.2147/ott.s242517